HIV-infected patients now live longer and often have complications of liver disease, especially with hepatitis B or C virus co-infection. Hepatocellular carcinoma (HCC) is an increasing cause of mortality in HIV positive and negative individuals. There is a lack of consensus regarding the clinical presentation, treatment options, and outcome in HIV-infected patients with HCC. Unfortunately, HCC is frequently diagnosed at an advanced stage, and mortality continues to be very high. Earlier diagnosis, which may allow potentially curative therapy, is necessary.

Liver resection is considered the most potentially curative treatment for HCC patients when liver transplantation is not an option or is not immediately accessible.

The aim of this article was to describe our liver resection strategy, describing our experience, for HCC in HIV infected patients.