Clear cell sarcoma mimicking a breast tumor in an elderly man: a rare case report and a literature review

WCRJ 2022; 9: e2250
DOI: 10.32113/wcrj_20223_2250

  Topic: Surgical oncology     Category:

Abstract

Objective: Clear Cell Sarcoma (CCS) is a rare tumor of mesenchymal origin accounting for 1% of soft tissue sarcomas (STS)1. Often misdiagnosed as malignant melanoma2 (MM), it has only one curative treatment: radical surgery and an extensive postoperative follow-up program2. Herein, we present a case of CCS mimicking a right breast tumor, where the patient´s age, gender, growth and localization of the neoplasm render it uncommon.

Case presentation: A 70-year-old male was admitted to the Surgery Department complaining about a 3-month right breast tumor. Ultrasound evidenced a nodular formation (2.29 cm-1.91 cm) and mammography showed a hyperdense image, projected 35 mm from the nipple, surrounded by calcifications. No signs of systemic disease were present. Core needle biopsy expressed histological characteristics compatible with both MM and CCS.

Results: After multidisciplinary team meeting, a wide resection surgery was performed followed by lymphadenectomy. The immunohistochemistry and pathology report led to the diagnosis: CCS.

Conclusions: CCS is a rare sarcoma with poor prognosis. This case is exceptional due to its epidemiology, unusual clinical manifestations and appearance, setting CCS up as a new differential diagnosis to keep in mind regarding breast tumors. Its extreme rarity could help other colleagues deal with this infrequent presentation.

To cite this article

Clear cell sarcoma mimicking a breast tumor in an elderly man: a rare case report and a literature review

WCRJ 2022; 9: e2250
DOI: 10.32113/wcrj_20223_2250

Publication History

Submission date: 08 Feb 2022

Revised on: 14 Feb 2022

Accepted on: 14 Mar 2022

Published online: 17 Mar 2022