Objective: The factors affecting the incidence of breast cancer are highly variable. The high prevalence of overweight and obesity, inappropriate lifestyle and socio-economic status are associated with breast cancer. Therefore, this study investigates morbidity, mortality, and association of breast cancer with Body Mass Index (BMI) and Human Development Index (HDI) in the Asian countries.

Materials and Methods: The study is based on the data acquired from the World Cancer Bank and World Bank (including HDI and its components). In this population-based study, we estimated the Population Attribution Frequency (PAF) by using the BMI in adult communities. The prevalence, mortality rates and distribution maps for breast cancer were extracted for different countries. Correlation and regression tests were used to analyze the data and examine the relationship between the prevalence and mortality with HDI. The statistical analysis of data was performed by Stata-14 and the significance level was considered as 0.05.

Results: The results showed that there is a positive and significant correlation between the incidence of breast cancer associated with the BMI and HDI (R=0.371, p <0.05). On the other hand, our findings showed that the higher the developmental index, the greater the percentage of breast cancer prevention associated with BMI. Moreover, there is a positive and significant correlation between the prevention and HDI (p = 0.522, p<0.05).

Conclusions: Obesity increases the likelihood of fatal cancer types and their recurrence, including BC. The risk of breast cancer in developed and developing countries, including the Asian countries, is increasing. Therefore, the modification of breast cancer risk factors needs to be emphasized to prevent it.