Sentinel lymph node navigation in gastric cancer

WCRJ 2018; 5 (4): e1172

  Topic: Surgical oncology     Category:

Abstract

Objective: This study aims to explore the application value and detection rate of sentinel lymph node (SLN) biopsy in accurate detecting of lymph node metastasis in patients with gastric cancer.

Patients and Methods: A total of 24 patients with Stage I, II or III gastric cancer, from 2015 to 2017, were admitted to our department and underwent D2-gastrectomy plus lymphadenectomy. All 236 nodes were sectioned and stained with immunohistochemical staining (IHC). Lymph node micro-metastasis was defined as evidencing to be positively stained or via the IHC process.

Results: The results indicated that gastric cancer stage 1 was significantly correlated with higher lymphatic metastasis.

Conclusions: Given the very low frequency of malignant non-sentinel lymph nodes was detected in stage 1, it could be logic and safe to merely dissected sentinel nodes without extended lymph node dissection while operation.

To cite this article

Sentinel lymph node navigation in gastric cancer

WCRJ 2018; 5 (4): e1172

Publication History

Submission date: 11 Aug 2018

Revised on: 29 Aug 2018

Accepted on: 17 Sep 2018

Published online: 04 Dec 2018