Special Issue on Hepatocellular Carcinoma

July 24, 2023

Hepatocellular carcinoma in the modern age: pathophysiological mechanism, genetic and epigenetic susceptibility, metabolic factors, and targeted therapy 

Dear Researchers, 

Liver cancer is the sixth common cancer and the second leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) accounts for ~90% of cases of liver cancer and is the fourth most common cause of cancer-related death in the world. HCC is often diagnosed at an advanced stage when treatment options may be limited and with poor prognosis. Thus, understanding the role of epigenetic, genetic, molecular mechanisms underlying HCC onset and progression is crucial for the development of newer targeted therapeutic strategies and to improve clinical outcomes. 

Given the complexity of this topic and its impact on clinical practice and public health, World Cancer Research Journal is launching a Special Issue entitled “Hepatocellular carcinoma in the modern age: pathophysiological mechanism, genetic and epigenetic susceptibility, metabolic factors, and targeted therapy” with the aim of gathering accurate and up-to-date scientific information on all aspects of the latest advances in HCC research. 

It is my privilege to invite you and your co-workers to share their experience and expertise by submitting original research articles, systematic reviews and review articles reporting new ideas and recent advances in this topic. 

Potential topics of interest include, but are not limited to: 

• HCC genomic and epigenomic; 
• Molecular mechanisms underlying HCC pathogenesis and progression; 
• Metabolic factors associated to HCC development and progression; 
• HCC targeted therapies;
• Diabetes and HCC.

Keywords: Human Hepatocellular Carcinoma (HCC), Immunotherapy, Cancer vaccine, Combination strategies, Epigenetic, Genetic, Metabolic disorders, Pathophysiological mechanisms. 

Guest Editors 

• Prof. Luca Rinaldi, University of Campania “Luigi Vanvitelli”, Naples, Italy. e-mail: lucarinaldi@hotmail.it

• Dr. Alfredo Caturano, Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy. e-mail: alfredo.caturano@virgilio.it

Deadline and Submission Guidelines

The submission deadline for all papers is March 31st, 2024.

Please, submit your article on https://www.publishingmanager.org/ by checking the box “Hepatocellular carcinoma in the modern age”. All articles will undergo a peer-review process as regularly submitted papers. Please, also check out our instructions for the authors before submission at the following link: https://www.wcrj.net/instructions-for-authors

For further information, please, contact the Publishing Manager by e-mail at matteo.gori@verduci.it